PROGRAMME

To view the Programme please click here. Some changes have been made since letters were written to authors allocating presentaion format. These changes are mainly alteration of allocated presentation numbers. Please check this programme regularly as further changes may be made. For your information a list of papers included in the programme follows :

PLENARY PRESENTATIONS
Wednesday 24 March 2010
PL01. TIA's Vision and Perspective
Dr Nhlanhla Msomi : Acting CEO, Technology Innovation Agency
PL02. Overview of Biotechnolgy in South Africa
 
Agro-Biotech
Dr. Antonio Llobell
 
Health Biotech
Dr Carl Montague
 
Industrial Biotech
Dr Dale Gyure
PL03: Friday 26 March at 15.20
White Biotechnology and Biocatalysis: New routes to chemicals from biomass?
C Syldatk : Karlsruhe Institute of Technology, Germany
ORAL & POSTER PRESENTATIONS
Thursday 25 March
SESSION 1
SYSTEMS BIOLOGY & MICROBIAL STRUCTURE
KN01. Discovering and developing drugs in South Africa: challenges and opportunities
Dr Kelly Chibale:
OR01. Making sense of omics data: computational tools for systems biology
JM Rohwera, L Uys, O Ebenhöh, M Schütte, E Kramer, M Stitt, J Hofmeyr: University of Stellenboch
OR02. Cell Wall-Omics - Tracking the careers of grape and wine polymers using biotechnology and systems biology
J Moore, EE Nguema-Ona, MA Vivier: Wine Institute, University ofStellenbosch
OR03. Cell walls and plant defense: using microscopical and analytical techniques to elucidate resistance phenotypes
E Nguema-Ona, JO Moore, M Vivier: Wine Institute, University ofStellenbosch
OR04. Investigating the mechanical properties of yeast cells: effect of generation age
J Stenson, STL Harrison: CeBER, University of CapeTown
SESSION 2A (parallel with Session 2B)
BIOPROCESS
OR05. Simulation based life cycle assessment and capital cost estimation to guide sustainable bioprocess development: substrate comparison in citric acid production as a case study
A de Beer, STL Harrison, K Harding: CeBER, University of CapeTown
OR06. Evaluation of techniques to quantify sessile populations in bioleach heaps
C Bryan, G Jones, N van Wyk, STL Harrison, RP van Hille: CeBER, University of CapeTown
OR07. KLa behaviour in aerated multiphase hydrocarbon-aqueous-solid systems.
M Manyuchi, R Voigt, KG Clarke: University ofStellenbosch
OR08. Recovery of antioxidants and process waster from table olive brines using membrane separation and chromatography
C Garcin : CeBER, University of CapeTown
SP01.The effect of temperature on the attachment of Metallosphaera sedula to a copper sulphide concentrate with application to heap bioleaching
L Bromfield, R van Hille, STL Harrison: CeBER, University of CapeTown
SP02. Production of surfactin, an antimicrobial biosurfactant produced by Bacillus subtilis ATCC 21332
K Bence, KG Clarke : University of Stellenbosch

SP03. Optimising microalgal lipid productivity for biodiesel production – direct transesterification as an assay for total fatty acid content
M Griffiths, DA Cowan, SG Burton, C Bressa: CeBER, University of CapeTown

SP04. tba
SESSION 2B (parallel with Session 2A)
METABOLISM & METABOLOMICS
OR09. Re-examining microarray probes to improve downstream analysis
E Alexandersson, D Jacobson, M Vivier: University Stellenbosch, Wine Institute
OR010. Carnitine supplementation has protective and detrimental effects in Saccharomyces cerevisiae that are genetically mediated
J Franken, FF Bauer : University Stellenbosch, Wine Institute
OR11. Metabolic profiling of photosynthetic pigments in transgenic grapevine
J Lashbrooke, PR Young, MA Vivier: University Stellenbosch, Wine Institute
OR12. Metagenomic sequencing and gene discovery
D Anderson, M Taylor, IM Tuffin, DA Cowan : University Western Cape, IMBM
OR13.Uptake and metabolism of luteolin-containing Artemisia afra aqueous-extract in Caco-2 cells
J Mukinda, JA Syce, D Fisher, M Meyer: Discipline of Pharmacology, University Western Cape
SP05. Metabolomic comparison of two commercial wine yeast strains
AH van den Dool, SG Villas-Bôas, FF Bauer: University Stellenbosch, Wine Institute
SP06. Metabolic profiling of volatiles produced during MLF fermentation: application of SPME GC-MS
A Tredoux , S Malherbe, HH Nieuwoudt, M du Toit : University Stellenbosch, Wine Institute
SESSION 3
GENERAL
KN02. Partnering to develop a Tuberculosis Drug Pipeline for South Africa: the Drug Discovery Strategy of the CBT/DST TB
P Terblanche : Medical Research Council
OR14. A new Master of Biotechnology proposed by CB-UEM (Mozambique) aimed at the sub-region.
E Boulange, M Colombo, A Ribeiro, R Pereira, L Neves : Universidade Eduardo Mondlane, Maputo
OR15. Setup and verification of a laser based immuno nephelometric assay to quantify Pneumococcal polysaccharide with reference to the vaccine manufacturing process.
N Swart: Biovac
SP07. Investigating the molecular and morphological response to process stress mediated through the presence of particulate phase using Saccharomyces cerevisiae as model system.
PY Hsu, STL Harrison : University Cape Town, CeBER
SP08.The impact of irrigation conditions on the development of microbial colonies in bioheaps
R Chiume, STL Harrison, S Minnaar : University Cape Town, CeBER
SP09. Actinobacterial populations inhabiting the Antarctic Dry Valleys mineral soils – a potential source of novel antimicrobial compounds.
B Kirby, SC Cary , IM Tuffin , DA Cowan : University Western Cape, IMBM
SP10. Isolation and characterisation of actinobacteria from a Zambian hot spring.
N Mavengere, B. Kirby, C. Syldatk, S. Burton, M Tuffin : University Western Cape, IMBM
SP11. The use of laccase for the production of beneficial novel antioxidant polymers.
A Parker, E Adelakun, N Murefu, R Zwane, SG Burton: Cape Peninsula University of Technology
SP12. ‘Deserted’ or in ‘hot soup’: The search for thermotolerant Actinobacterial tyrosinases.
W Mavengere, A Casanueva, M Le Roes-Hill, S Burton, MI Tuffin, DA Cowan : University Western Cape, IMBM
SP13. Genomic and morphological characterisation of a novel Antarctic prophage.
T Meiring, M Tuffin, C Cary, DA Cowan: University Western Cape, IMBM
SP14. Expression of rotavirus capsid proteins in N. benthamiana plant leaves.
DL Mutepfa, II Hitzeroth, EP Rybicki : Molecular & Cell Biology, University Cape Town
SP15. A critical evaluation of CO2 supplementation to algal systems by direct injection.
N Langley, STL Harrison, RP van Hille : University Cape Town, CeBER
Friday 26 March
SESSION 4A (parallel with Session 4B)
ENVIRONMENTAL PROCESSES
OR16. Production of industrially important peroxidases from actinobacteria isolated from various environments.
N Khan, M Le Roes-Hill, DA Cowan, SG Burton: Cape Peninsula University of Technology
OR17. Biokinetic investigation of the integrated management mineral sulfide ore waste.
A Hesketh, STL Harrison : University Cape Town, CeBER
OR18. Optimisation of the biological sulphate reduction: investigating the effectof reactor configuration.
O Oyekola, RP van Hille, STL Harrison : University Cape Town, CeBER
OR19. Bioremediation of metal contamination in the Plankenburg River, Western Cape, South Africa.
V Jackson et al : Cape Peninsula University of Technology
OR20. Biotech in sanitation: polymers from wastewater.
B Verster, B Cohen, STL Harrison : University Cape Town, CeBER
OR21. Molecular survey of constructed wetland microbial communities impacted by winery-effluents.
J-B Ramond, PJ Weltz, SG Burton, M Tuffin : University Western Cape, IMBM
SESSION 4B (parallel with Session 4)
PROTEOMICS
KN03. Atomic Details of Infectious Diseases.
W-D Schubert: University Western Cape
OR22. Monitoring vaccine responses in clinical trails using protein array technologies.
J Blackburn : University Cape Town IIDMM
OR23. Optimising a proteomics approach to evaluate grapevine berry suspension cultures.
R Govind, C Stander, B Ndimba, M Vivier : University Stellenbosch, Wine Institute
OR24. Oxidative enzymes from Actinomycetes: a focus on new tyrosinases with industrial potential.
M Le-Roes Hill, B Kirby, J Rohland, P Meyers , DA Cowan, SG Burton : Cape Peninsula University of Technology

SP16. Crystal structure of the large glutamine synthetase from Bacteroides fragilis.
J van Rooyen, VR Abratt, H Belrhali, BT Sewell : University Cape Town, Molecular & Cell Biology

SP17. Exploring structure-function relationships in p450 enzymes: en route to in silico predictions of the effect of polymorphic variation on drug metabolism
L Coulson, N Beeton-Kempen, A Zawaira, J Blackburn: University Cape Town IIDMM
SP18. Sequencing and partial characterisation of a lipolytic enzyme from an estuarine metagenomic library
T Nyman, DA Anderson, C Heath, MI Tuffin, DA Cowan: University Western Cape, IMBM
SESSION 5A (parallel with Session 5B)
BIOINFORMATICS
KN04. South Africa’s National Bioinformatics Initiatives: Can we deliver in this post-genomic era?
A Christoffels : SANBI
OR25. Comparing the transcriptomes of wine yeast strains: towards understanding the interaction between environment and transcriptome during fermentation.
D Rossouw, F Bauer : University Stellenbosch, Wine Institute
OR26. Genetic strategies to control cell adhesion of Saccharomyces cerevisiae
M Bester, FF Bauer, D Jacobson: University Stellenbosch, Wine Institute
OR27. Bioinformatics capacity at the CPGR
J Kumuthini : Centre for Proteomic and Genomic Research

OR28. Genomics of quantitative disease resistance in African maize varieties.
S Murray et al: Centre for Proteomic and Genomic Research

SESSION 5B (parallel with Session 5A)
PROTEIN EXPRESSION
OR29. Lignocellulose conversion to fuel: Taking a high-throughput shortcut across the metagenomic highway.
C Ohlhoff, A Casanueva, R Huddy, I Mulako, R Bauer, DG Cowan, M Tuffin: University Western Cape, IMBM
OR30 . Expression and optimisation of Human papillomavirus type 16 (HPV 16) chimaera candidate vaccines in Nicotiana benthamiana.
C Pineo : University Cape Town, Molecular & Cell Biology
OR31. Intein-mediated expression allows for the production of biologically active plant defensin peptides in Escherichia coli
Abré de Beer, M Vivier:
University Stellenbosch, Wine Institute
OR32. Discovery of two novel cold-active esterases from Antarctic soil using metagenomics.
XP Hu, C Heath, M Taylor, M Tuffin, DA Cowan: University Western Cape, IMBM
OR33. Production of industrially relevant heterologous proteins in yeasts and filamentous fungi.
R den Haan, DC la Grange, SH Rose, JF Gorgens, WH van Zyl: University Stellenbosch, Microbiology
OR34. Heterologous expression of cytochrome P450 monooxygenases in E. coli and yeasts.
M Smit : University of the Free State
SESSION 6
BIOPROCESS & BIOTRANSFORMATIONS
OR35. Effects of site-directed mutagenesis on the substrate specificity of a thermostable nitrile hydratase
P Griffiths, DA Cowan, SG Burton, C Bressa: Cape Peninsula University of Technology
OR36. Real-time bioprocess monitoring of alcoholic fermentation: application of Fourier transform mid infrared (FTIR) spectroscopy
H Nieuwoudt, CM Magerman: University Stellenbosch, Wine Institute
OR37. Development of an assay system for external carbonic anhydrase activity in whole cell algal systems
R van Hille, R Dicks, M Fagan, R Pott : University Cape Town, CeBER
OR38. New natural antioxidants and in vivo demonstration of their protective effects on health
S Burton, L Davids, N Chigorimbo-Tsikiwa, R Zwane: Cape Peninsula University of Technology
PL03. White Biotechnology and Biocatalysis: New routes to chemicals from biomass?
C Syldatk : Karlsruhe Institute of Technology, Germany
POSTER PRESENTATIONS
PP01. Characterization of fluconazole-resistant and -susceptible oral Candida isolates from HIV-Positive Patients Using SDS-PAGE.
PA Abrantes, R Fisher, PJD Bouic, CWJ Africa: UWC, Medical Bioscience
PP02. Chromium tolerance and reduction potential of Staphylococci species isolated from a fly ash dumping site in South Africa.
C Kouadjo, L Van Zyl, M Tuffin, D Cowan, A Zeze: University Western Cape, IMBM
PP03. Energy recovery from biodiesel residues by anaerobic digestion.
A Inglesby, S Harrison and R van Hille: University Cape Town, CeBER
PP04. Characterization of enzymes involved in 2,3 Butanediol pathways.
L Adonis, D Barnard, M Tuffin, DA Cowan: University Western Cape, IMBM
PP05. The uniqueness of mycothiol in M. tuberculosis. Is it really necessary for intracellular survival?
J Mazorodze, A Jardine, C Chastellier, B Baker: University Cape Town, Molecular & Cell Biology
PP06. The isolation and characterisation of thermophilic esterases from Actinomycetes for application in lignocellulose digestion.
M Oldale, S Easton, M. Le Roes-Hill, SG Burton, R Bauer, M Tuffin, DA Cowan: University Western Cape, IMBM
PP07. Screening for α-L-arabinofuranosidases from thermophilic Actinomycetes for the digestion of lignocellulosic feedstocks for biofuel production.
LA Matthews, M Le Roes, SG Burton, R Bauer, IM Tuffin. DA Cowan: University Western Cape, IMBM
PP08. The identification and characterization of thermophilic lignin degrading peroxidases from Actinomycetes for use in biofuel production.
R Crisp, A Casanueva , M Le Roes-Hill, SG Burton, R Bauer, DA Cowan, IM Tuffin: University Western Cape, IMBM
PP09. Isolation and morphological diversity of bacteriophages from Antarctic cold desert environments.
K Lukusa, T Meiring, C Cary, IM Tuffin, DA Cowan: University Western Cape, IMBM
PP10. Role of water availability in Antarctic desert microbial community structure and function.
D Booysen, M Mutondo, DA Cowan: University Western Cape, IMBM

PP11. Screening for Lignocellulosic Enzymes using a Metagenomic Approach.
T January, XP Hu, R Bauer, S Fall, R Huddy, I Mulako, M Taylor, M Tuffin. DA Cowan.: University Western Cape, IMBM

PP12. Identification of sorghum secretome using proteomics tools
R Ngara, B Ndimba : University Western Cape/Biotechnology
PP13. Comparative proteome analysis of wild type and codA transgenic Arabidopsis plants.
N Ndabambi, B Ndimba: University Western Cape/Biotechnology
PP14. Molecular screening of wine lactic acid bacteria enzymes using gene-specific primers.
PS Mtshali, B. Divol, M. Du Toit: University Stellenbosch, Wine Institute
PP15. Yeast protein release and haze formation during aging in model wine.
T Ndlovu, JO Moore, B Divol, FF Bauer: University Stellenbosch, Wine Institute
PP16. Production and immunogenicity of a prophylactic and therapeutic vaccine to protect against multiple human papillomavirus types.
M Burger, GK de Villiers, II Hitzeroth, EP Rybicki: University Cape Town, Molecular & Cell Biology
PP17. A simple method for high throughput analysis of volatiles in wine.
A Tredoux : University Stellenbosch, Wine Institute
PP18. High throughput screening of wine metabolites using Fourier transform infrared spectroscopy in attenuated total reflection mode (FTIR-ATR)
HH Nieuwoudt, J Moolman, L Coetzee, N Oosthuizen, P Norval: University Stellenbosch, Wine Institute
PP19. The expression of fungal enzymes in Saccharomyces cerevisiae for raw starch degradation.
M Viktor, M Bloom, WH van Zyl: University Stellenbosch, Microbiology
PP20. Microbial population changes is reponse to amendment with winery wastewater and ethanol in pilot-scale constructed wetlands.
P Welz, J-B Ramond, D Cowan, SG Burton: Cape Peninsula University of Technology
PP21. Development and optimisation of a bioreactor system to reduce the level of bacterial contaminants in the Plankenburg River in the Western Cape.
AN Paulse, VA Jackson, JH Neethling, AA Bester, W. Khan: Cape Peninsula University of Technology
PP22. Isolation of a novel Cytosolic Malate Dehydrogenase (MDH) in Lupinus angustifolius.
M le Roux, AJ Valentine, S Khan: Cape Peninsula University of Technology
PP23. Detection and isolation of pathogenic bacteria from river water.
MR Manesen, W Khan, S. Khan: Cape Peninsula University of Technology
PP24. Comparison of two techniques for the qualitative detection of Adenoviral contamination in two rivers in the Western Cape, South Africa.
M Saayman, M Tobin, W Khan, S Khan: Cape Peninsula University of Technology
PP25. Beneficiation of citrus and deciduous fruit wastes.
K Horne, SG Burton: Cape Peninsula University of Technology
PP26. Modeling airlift photobioreactors for algae cultivation.
M Fraser, STL Harrison: University Cape Town, CeBER
PP27. Investigating Anthocyanin production in two phenotypes of 'Bon Rouge' Pyrus communis, L. by high throughput transcriptome sequencing.
M du Preez, DJG Rees: University Western Cape, Biotechnology
PP28. Characterisation and screening of a novel actinobacterial isolated for thermophilic lignocellulosic enzymes
Yu Gao, R Bauer, R Huddy, M Tuffin, DA Cowan. : University Western Cape, IMBM

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